Urinary stones affect 10-12% of the population in industrialized countries. There are only a few geographical areas in which stone disease is rare. Among the treatments used are extracorporeal shock wave lithotripsy (ESWL) and drug treatment. Even improved and besides the high cost that imposes, compelling data now suggest that exposure to shock waves in therapeutic doses may cause acute renal injury, decrease in renal function and an increase in stone recurrence. Data from in-vitro, in-vivo and clinical trials reveal that phytotherapeutic agents are useful as either an alternative or an adjunctive therapy in the management of urolithiasis mainly due to the presence of constituents like flavonoids which are potent antioxidants and reduce the oxidative stress on kidneys. This review article is about the drugs containing flavonoids which have potential use in urolithiasis.
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